CJC-1295 / Ipamorelin

This is a great combination of peptides for enhancing intrinsic growth hormone production participate in achieving anti-aging and wellness benefits.

This combination is used as a subcutaneous injection as prescribed which helps with the following:

• Energy and well-being
• Improved bone mineral density
• Increased lean body mass
• Post-surgical wound healing
• Body repair and recovery
• Better Sleep Quality

Sermorelin

Sermorelin is not HGH, it is a growth hormone secretagogues (GSHs) which is a class of molecules that stimulates the secretion of GH from the pituitary gland. Sermorelin therapy is a gradual anti-aging therapy that can take a few months before the effects start to become noticeable, although many patients experience positive health effects within just days or weeks of starting the therapy.

It is available for subcutaneous injection and assists with the following goals.

• Increased lean body mass
• Fat reduction
• Improved energy
• Increased vitality, strength, and endurance
• Accelerated wound healing
• Improved cardiovascular and immune function
• Better sleep quality
• Improved bone density, skin quality and higher collagen density

Kisspeptin-10

Kisspeptin has recently emerged as a central regulator of gonadotropin function playing key role in puberty and reproductive hormone function.

Most recent findings are as follows.

• Vital for puberty, and fertility by gonadotropin secretion
• Regulating energy expenditure and obesity

Bremelanotide (PT-141)

PT-141 modulates brain pathways involved in sexual response possibly via stimulating dopamine release and found to be equally effective in men (ED) and women (FSD).

Effective in treating sexual dysfunction in men:

• Impotence / erectile dysfunction and
• Premature ejaculation

In women the areas of clinical use are:

• HSDD (Hypoactive Sexual Desire disorder) and
• FSAD (Female Sexual Arousal Disorder)

5-Amino-1MQ

5-Amino-1MQ is a small, selective, membrane permeable molecule that is an inhibitor of nicotinamide N-methyltransferase (NNMT), a cytosolic enzyme that plays a role in cellular metabolism and energy homeostasis. NNMT has been found to be up-regulated in white adipose tissue of mice compared to other tissues, thus, NNMT is an ideal target for anti-obesity medication. 5-amino-1MQ is a derivative of methylquinolinium (MQ) which has exhibited a high efficacy in NNMT inhibition, cell viability, and membrane permeability. It did not have any effect on the activity of any other enzymes in the relevant metabolic cycles, therefore reducing the risks of potential side effects. This NNMT inhibitor could be used to prevent adipogenesis and type II diabetes and reverse diet-induced obesity as a result of increased intracellular NAD+ and SAM.

In a study using diet-induced obese mice fed a high fat diet, the effects of 5-amino-1MQ on obesity measures and plasma lipid were evaluated. After 11 days, mice treated with 5-amino-1MQ lost weight, exhibited a decrease in white adipose mass and cholesterol levels, and displayed reduced lipogenesis. The results of this study validate NNMT as a practical target to treat obesity and related metabolic conditions and support the development of an NNMT inhibitor therapeutics to reverse diet-induced obesity.

ARA-290 Inj

ARA-290 is a peptide currently being researched for its safety and efficacy for the treatment of neuropathic pain in patients with sarcoidosis, as well as its potential for disease modification and long-term functional improvement in this condition.

BPC-157

Pentadecapeptide BPC 157, composed of 15 amino acids, is a partial sequence of body protection compound (BPC) that is discovered in and isolated from human gastric juice. Experimentally it has been demonstrated to accelerate the healing of many different wounds, including tendon-to-bone healing and superior healing of damaged ligaments.

Additionally, BPC 157 has shown to protect organs and aids in the prevention of gastric ulcers. BPC-157 acts systemically in the digestive tract to combat leaky gut, IBS, gastro-intestinal cramps, and Crohn’s disease.

This peptide has been known to exhibit analgesic characteristics. Those who suffer from discomfort due to muscle sprains, tears and damage may benefit from treatment with this peptide. It can also help to aid skin burns at a faster rate by increasing blood flow to damaged tissues.

MK-677

MK-677 is a long active orally bioactive agonist of the GHS-R1a. As such, binds to the same receptor that GHRP2, GHRP6, and Ipamorelin also stimulate. Also called Ibutamoren, it has shown to cause a predictable rise in IGF-1 but unlike other GH secretagogues doesn’t help to decrease adipose tissue. It has been shown to increase lean muscle mass and might be a good candidate for sarcopenic patients with low bone mineral density. In order to reduce the negative effect of somatostatin, MK-677 is best taken on an empty stomach with no insulin in the system.

SELANK

Selank is another ACTH/MSH-like peptide of the melanocortin class most closely related to the analog tufstin. While traditionally prescribed for anxiety and depression, it has been known to be effective in many other treatments related to immune modulation, anticoagulation, PTSD, ADHD, and metabolic syndromes. Selank has pronounced anxiolytic activity and acts as a stable neuropsychotropic, antidepressant, and anti-stress drug that relieves aggression and fear reaction in different animal species. Selank also has a nootropic action, which positively influences the formation of memory and learning processes, and marked immunomodulatory activity. Clinical studies have shown that the effect of selank is similar to that of tranquilizers at low doses, but is not accompanied by the unwanted side effects of benzodiazepine tranquilizers such as amnesia, withdrawal, or dependence. Experiments have also demonstrated the effectiveness of Selank in preventing the accumulation of body fat (i.e., weight gain) with simultaneous activation of the functional state of the anticoagulation system in development of the metabolic syndrome.

Furthermore, decreased blood glucose levels have been observed with chronic treatment of this peptide. The peptide Selank, like the drug Semax, induces anticoagulant and hyperglycemia effects possibly due to the presence of the same amino acid sequence, Pro-Gly-Pro, in its structure. Thus, Selank can be used as a broad-spectrum therapeutic agent for the treatment of metabolic syndrome. Often prescribed for: Anxiolytic, Immune improvement, gastric protection, as a preventative weight gain/metabolic syndrome, and with opioid and alcohol withdrawal/ dependence.

SEMAX

It is well known that ACTH/MSH-like peptides (melanocortins) exert pleiotropic non-hormonal actions among their larger activities. Melanocortins affect learning processes and exploratory behavior, regeneration and development, nociceptive and inflammatory processes, accelerate nerve regeneration and improve neuromuscular performance. Together these classes of peptides control many behaviors such as regulating attention, processes of learning, and memory formation as a result of their pronounced effect on CNS functions. Heptapeptide SEMAX (MEHFPGP) is the analogue of ACTH (4-10) that has prolonged neurotropic activity and thus is a good candidate for medical therapy. Currently this peptide is successfully used in treatment of patients with pathologies related to brain circulation dysfunction and with different intellectual-amnestic problems of the CNS. Doctors have prescribed it for many conditions like anxiety, memory improvement, ischemic events, stroke, nerve regeneration, ADHD, opioid withdrawal, and even Chronic diseases such as ALS, Parkinson’s, and Alzheimer’s. Some doctors use it as a preventative measure to protect against chronic disease and to acutely help improve memory and learning processes. It also has a marked antithrombotic and fibrinolytic effect and a gastric protective effect. It has also been suggested in literature that due to its effect on carboxypeptidase it can also increase physical performance and adaptation capacities in exposure to high intensity exercise. At its higher doses, .5mg/kg can even be analgesic.

Often prescribed for: Anti-Thrombosis, ADHD/Learning, Gastric protection, Physical exertion improvement pain, Metal toxicities.